Hi Yes, you can do a one-way bike rental from Manali to Leh, but it's important to be aware of a few things: Cost: One-way rentals are generally more expensive than round-trip rentals. Expect to pay a drop-off fee on top of the daily rental rate. This can range from Rs. 8,000 to Rs. 10,000 Leh Restrictions: Leh Ladakh Bike Union rules may restrict using a Manali-rented bike for sightseeing within Ladakh. You might need to rent another bike in Leh for that purpose.